"X-Machine Model of a Biological System"

Supervised by Professor WM Holcombe

Abstract

This project is in the field of computational biology, by using the computer simulation model to display the biological systems' spatial and temporal aspects in detail.

The aim for this project is develop a simulation of a vital part of the immune system by using xmachine framework and tools such as xparser and xml. By converting the exist models in Matlab code into xml, and then use an xparser parse it to a runnable C source coded programme.

Three models are involved in this project: chemical interaction model, NF-kB signalling pathway model and NF-kB & MAP kinase signalling combined model. The first two models have exist Matlab model to be converted, but the last model is needed to do some research and add a new pathway into NF-kB.