The University of Sheffield
Department of Computer Science

Simon Wood Undergraduate Dissertation 2015/16

Development of an Agent-Based Model of Cellular Interactions in Multiple Myeloma (DW-UG-4)

Supervised by D.Walker

Abstract

Multiple myeloma  is a cancer of the bone. It's effects are well understood in a physical sense but not in a mathematical one. The creation of an experimental model could lead to new research in this area, as a viable model of a human biological system can be used to run many experimental procedures and treatments that would otherwise be ethically impossible. Such a model could also lead to new understanding of the quantitative processes that operate in the human body. While this project will probably not achieve that, it can certainly exist as the building block for a much more in dept and refined system.

This project aims to investigate the merits of using agent-based model systems in order to examine and experiment on a simulation of the biological system of multiple myeloma  in bone. The hope is that a suitable model can be created, or at the very least that it can be ascertained whether or not such a model would be a worthwhile computational system to have.